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Peptide Dose by Body Weight Calculator

✓ Editorially reviewed by Derek Giordano, Founder & Editor · BA Business Marketing

Last reviewed: January 2026

When protocols specify mcg/kg, enter your weight and dose-per-kg to calculate your total dose and exact syringe draw.

mcg total daily dose
mcg per injection
IU to draw (100-unit syringe)
days per vial
📊 Common Weight-Based Peptide Dosing Reference
PeptideLow Dose (mcg/kg)Standard (mcg/kg)High (mcg/kg)Notes
BPC-1571–2 mcg/kg3–5 mcg/kg7–10 mcg/kgMost studies use 10 mcg/kg in animals; human equiv ~1–2 mcg/kg
Sermorelin0.5 mcg/kg1–2 mcg/kg3 mcg/kgPediatric dosing standard; adult protocol often flat 200–500 mcg
IGF-1 LR30.3 mcg/kg0.5–1 mcg/kg1.5 mcg/kgVery potent — start at low end; max ~100 mcg/day absolute
Epithalon0.05 mcg/kg0.1 mcg/kg0.15 mcg/kgOften expressed as flat 5–10 mg/course; weight-based less common
GHK-Cu0.01 mcg/kg0.02 mcg/kg0.03 mcg/kgMost protocols use flat dosing (1–2 mg/day); weight-based in research
PT-1410.006 mcg/kg0.012 mcg/kg0.025 mcg/kgFDA-approved dose is flat 1.75 mg; weight-based in older trials
KPV2 mcg/kg5 mcg/kg10 mcg/kgAnti-inflammatory; flat dosing (250–500 mcg) also standard
*These are research reference ranges. Always follow your prescribing clinician's specific protocol.
⚠️ Research use only. Not medical advice. Weight-based dosing protocols must be determined by a qualified healthcare provider familiar with your individual health status.

How to Use This Calculator

  1. Enter your body weight — Input your weight in pounds or kilograms. The calculator converts automatically if needed.
  2. Select the peptide — Choose the peptide you're calculating for — each has different weight-based dosing ranges established in research literature.
  3. Review the mcg/kg dose range — The calculator shows the low, moderate, and high dose based on your body weight. Research-referenced dose ranges help you understand where typical protocols fall.
  4. Calculate the injection volume — After determining your dose in mcg, the calculator shows the corresponding injection volume based on your reconstitution concentration.

Tips and Best Practices

Use this as an educational reference. Peptide dosing information is provided for research and educational purposes. Always consult a healthcare provider before starting any peptide protocol.

Double-check your math. Small reconstitution or dosing errors can significantly affect concentration. Verify your calculations before drawing a dose.

Bookmark for repeat reference. Peptide calculations are needed every time you reconstitute a new vial — save this page for quick access.

Explore related peptide tools. Use this alongside the other peptide calculators on the site for a complete protocol planning workflow.

Tips and Best Practices

Use this as a starting point, not a diagnosis. Online calculators provide estimates based on population averages. Your individual results may vary — consult a healthcare professional for personalized medical advice.

Measure consistently. For the most accurate tracking, take measurements at the same time of day under the same conditions each time you use this calculator.

Track trends, not single data points. One measurement is a snapshot. Track results over weeks and months to see meaningful patterns and progress.

Combine with related tools. Use this alongside other health calculators on this site for a more complete picture of your fitness and wellness metrics.

See also: Peptide Storage Calculator · GLP-1 Titration Tracker · Sweat Rate & Hydration Calculator · Body Surface Area Calculator · Exercise Calorie Burn

📚 Source: FDA: Drug Information

What Is a Peptide Dose by Body Weight Calculator?

A peptide dose by body weight calculator converts a research-protocol dose expressed in mcg per kilogram (mcg/kg) into the actual milligrams or micrograms you'd draw for a person of a specific weight, and then converts that into a syringe-volume measurement based on your reconstitution. The math is simple but easy to make mistakes on under fatigue or distraction, especially when you're working across three different units of measurement (kg ↔ lb, mcg ↔ mg, mL ↔ IU on an insulin syringe). The calculator catches these conversion errors before they become injection errors.1

Body weight scaling matters because most peptides reach their target tissues through the systemic circulation. A 60 kg person and a 110 kg person who both inject 250 mcg of BPC-157 reach noticeably different plasma concentrations — the lighter person sees roughly 1.8× the concentration. For peptides with a wide therapeutic window this might not matter much, but for compounds where benefit and side-effect dose ranges overlap, weight-scaled dosing is the safer default. This is why most published research protocols and clinical-trial protocols specify mcg/kg or mg/kg rather than a flat dose.

How mcg/kg Dosing Works

StepWhat you provideWhat the calculator computes
1. Convert weightBody weight (lb or kg)Weight in kilograms
2. Apply protocolDose-per-kg from your sourceTotal dose in mcg
3. Apply concentrationVial size and BAC water volumemcg per mL after reconstitution
4. Compute drawVolume in mL and units on insulin syringe

The most error-prone conversion is step 4. A standard U-100 insulin syringe is marked in "units" — but those units are based on insulin concentration (100 IU/mL), so 1 mL = 100 units. Drawing "20 units" means drawing 0.2 mL. If your peptide is reconstituted at 1 mg in 2 mL of bacteriostatic water, that's 500 mcg/mL, so 20 units = 0.2 mL = 100 mcg. The calculator handles this automatically once you enter vial size and water volume.

Common Weight-Based Dosing Ranges

The protocols below are summarized from published research and reported clinical practice. They are illustrative — your specific protocol should come from your physician or from the source paper for your compound of interest.

PeptideTypical research rangeNotes
BPC-1572.5–10 mcg/kg twice dailyOften quoted as 250–500 mcg flat per dose
TB-5002.0–4.0 mg twice weekly (loading); 2.0 mg weekly (maintenance)Often dosed flat rather than per-kg
Sermorelin1–5 mcg/kg eveningOnce daily, fasted, before sleep
CJC-1295 (no DAC)1–2 mcg/kg per dose, 2–3×/dayUsually paired with a GHRP
Ipamorelin1–3 mcg/kg per dose, 2–3×/dayPulse dosing, fasted preferred
IGF-1 LR30.5–2.0 mcg/kg dailyNarrow therapeutic window — start low
Tesamorelin~25 mcg/kg dailyApproved at 2 mg flat dose for HIV-related lipodystrophy

Worked Example

Suppose you weigh 175 lb and your protocol calls for BPC-157 at 5 mcg/kg twice daily. You have a 5 mg vial reconstituted with 2 mL of bacteriostatic water.

  1. Weight conversion: 175 lb ÷ 2.2046 = 79.4 kg.
  2. Per-dose calculation: 79.4 kg × 5 mcg/kg = 397 mcg per dose.
  3. Concentration: 5 mg ÷ 2 mL = 2,500 mcg/mL.
  4. Volume to draw: 397 mcg ÷ 2,500 mcg/mL = 0.159 mL.
  5. Insulin syringe units: 0.159 mL × 100 = 15.9 units. Round to 16 units.

That single dose comes from a fraction of one milliliter — which is why precision matters. A 4-unit difference (drawing 20 instead of 16) is a 25% dose error.

Why Reconstitution Concentration Matters

The same vial of peptide reconstituted with different volumes of bacteriostatic water produces different concentrations and therefore different syringe draws. A 5 mg vial diluted in 1 mL gives 5,000 mcg/mL — for a 397 mcg dose, that's 8 units on an insulin syringe, hard to draw accurately because small variations are amplified. The same 5 mg vial diluted in 5 mL gives 1,000 mcg/mL — the same 397 mcg dose is 40 units, which is much easier to measure precisely. The trade-off: more dilute solutions take up more space in the vial and require larger injection volumes for higher doses. A common sweet spot is 2 mL water for a 5 mg vial, giving doses in the 10–50 unit range for typical body weights and protocols. See our Peptide Reconstitution Calculator for diluent planning.

Pounds vs Kilograms

This is the most common arithmetic error. The conversion is 1 kg = 2.2046 lb. To convert pounds to kilograms, divide by 2.2046 (or roughly by 2.2). To convert kilograms to pounds, multiply by 2.2046. Worked examples: 150 lb = 68 kg, 180 lb = 81.6 kg, 200 lb = 90.7 kg, 220 lb = 99.8 kg. Doing this conversion by hand under fatigue is where dose errors creep in — using a calculator is not optional for any precision-sensitive peptide.

When Flat Dosing Is Used Instead

Not every peptide protocol uses weight-based dosing. Tirzepatide and semaglutide for type 2 diabetes and obesity are titrated flat doses (e.g., 2.5 mg → 5 mg → 7.5 mg → 10 mg over weeks regardless of body weight). Tesamorelin is approved at 2 mg per day flat. Many GHRP protocols specify flat doses (e.g., 100 mcg or 200 mcg of Ipamorelin per pulse) because the dose-response curve is shallow within a normal adult body-weight range. The general rule: peptides with narrow therapeutic windows or strong dose-dependent side-effect profiles tend to use weight-based dosing; peptides with wide windows often use flat dosing for protocol simplicity.2

Common Dosing Mistakes

Mixing up mg and mcg. 1 mg = 1,000 mcg. A 1 mg dose is one thousand times larger than a 1 mcg dose. If your protocol says 250 mcg and you accidentally read it as 250 mg, you'd be administering 1,000× the intended dose. Always double-check unit symbols, especially in handwritten or quickly-typed notes.

Forgetting the BAC water dilution. Your vial is labeled "5 mg" but the syringe draws from a solution. Always factor in your reconstitution volume — 5 mg in 1 mL is five times more concentrated per unit volume than 5 mg in 5 mL.

Using wrong syringe units. U-100 insulin syringes (100 units = 1 mL) are standard for SQ peptide injection. U-40 insulin syringes (used for some veterinary insulin) read differently — 100 units on a U-40 syringe is 2.5 mL, which would be 2.5× the intended dose. Verify your syringe is U-100.

Rounding aggressively to whole units. Calculated dose of 6.4 units rounds to 6 — that's a 6.25% under-dose. For peptides where precision matters, draw between two marks or use a smaller-graduation syringe (some U-100 1/2-unit syringes exist).

Why is peptide dosing based on body weight?
Body weight dosing ensures more consistent plasma concentration across different body sizes. A 60 kg person and a 110 kg person who both inject 250 mcg of the same peptide reach noticeably different plasma concentrations — roughly 1.8× higher for the lighter person. For peptides where benefit and side-effect dose ranges overlap, weight-scaled dosing is the safer default. This is why most published research and clinical-trial protocols specify mcg/kg rather than flat doses.
What units are peptide doses measured in?
Peptide doses are typically expressed in micrograms (mcg) or milligrams (mg) — 1 mg equals 1,000 mcg. Research doses are often expressed as mcg per kg of body weight. After reconstitution, the dose is administered as a volume (in mL or "units" on an insulin syringe), where 100 units on a standard U-100 insulin syringe equals 1 mL. The conversion from mcg to volume depends on your reconstitution concentration. See the Peptide Reconstitution Calculator for the full dilution math.
How do I convert pounds to kilograms for dosing?
Divide pounds by 2.2046 to get kilograms. For quick mental math you can divide by 2.2 — the difference is less than 1%. Examples: 150 lb = 68 kg, 180 lb = 81.6 kg, 200 lb = 90.7 kg, 220 lb = 99.8 kg. Use the calculator above for any precision-sensitive protocol — manual conversion under fatigue is the most common source of dose errors.
What if my protocol uses flat dosing instead of mcg/kg?
Many protocols specify flat doses (e.g., "250 mcg twice daily" rather than "5 mcg/kg twice daily"). Flat dosing is common for peptides with wide therapeutic windows — Ipamorelin, Sermorelin, and most GHRP protocols are often expressed this way for simplicity. For these, just enter the flat dose directly and skip the body-weight scaling. Tirzepatide, semaglutide, and tesamorelin are also flat-dosed in their approved indications.
How precise does my dose need to be?
It depends on the peptide. For BPC-157 and other healing peptides with wide therapeutic windows, ±10% is generally acceptable. For IGF-1 LR3 and other compounds with narrow windows, aim for ±5% or better. For tirzepatide and semaglutide where titration matters, follow the prescribed step exactly — these are dosed in 0.25–0.5 mg increments specifically because precision matters. When in doubt, use a 1/2-unit insulin syringe and round to the nearest 1/2 unit rather than whole units.
Should I dose based on lean body mass instead of total body weight?
For most peptides, total body weight is what's used in published research and is the simplest and safest default. Some growth hormone protocols informally suggest scaling to lean body mass for very high-body-fat individuals because peptide distribution is largely to lean tissue, not adipose. This is more nuance than most users need — total body weight, used consistently, will produce predictable results that you can adjust based on your response over the first 2–4 weeks of a cycle.
Editorial Standards — Every calculator is built from peer-reviewed formulas and official data sources, editorially reviewed for accuracy, and updated regularly. Read our full methodology · About the author