🩹

BPC-157 (Body Protection Compound-157)

✍️ Reviewed by nnng.com Editorial Team · April 2026 · Medical disclaimer

The body's own repair peptide — accelerates healing of muscle, tendon, gut, and nerve tissue.

📍 Healing & Recovery ⏱ 1–2× daily 💉 SubQ (systemic) or IM (local) 🔄 Cycle: 4–12 weeks ⏳ Half-life: ~4 hours ❄️ Storage: 30 days refrigerated

📋 What is BPC-157?

BPC-157 is a synthetic pentadecapeptide derived from a protein found in human gastric juice. It is one of the most researched peptides for healing and recovery, with studies showing accelerated healing of tendons, ligaments, muscles, bones, and the gastrointestinal tract.

Mechanism: BPC-157 promotes angiogenesis (new blood vessel formation), upregulates growth hormone receptors in tendon fibroblasts, and modulates nitric oxide systems. It appears to act as a systemic tendon-to-bone healing accelerator.

✅ Key Benefits

Accelerated tendon and ligament healing
Muscle repair and reduced inflammation
Gut healing — ulcers, IBD, leaky gut
Nerve regeneration and neuroprotection
Bone healing and remodeling
Reduced systemic inflammation

🧬 BPC-157 Reconstitution Calculator

Vial Size (mg)

BAC Water (mL)

Dose (mcg)

—

IU to draw on 100-unit syringe

— mL

Concentration: —

Open full calculator with BPC-157 pre-loaded →

⚠️ Research use only. Not medical advice. Consult a licensed healthcare provider before using any peptide.

💉 Dosing Reference Table

Goal	Dose	Frequency	Route
Systemic healing / general	250 mcg	2× daily	SubQ abdomen
Local injury (tendon/muscle)	200–400 mcg	1–2× daily	IM near site
Gut health / IBD	250 mcg	2× daily	SubQ or oral
Nerve repair	250–500 mcg	2× daily	SubQ
Maintenance / preventive	200 mcg	1× daily	SubQ

Standard protocol: 250 mcg SubQ twice daily for 4–8 weeks. For acute injury: start at 400–500 mcg 2× daily for the first 2 weeks, then reduce to 250 mcg. Oral BPC-157 (capsule form) has shown efficacy for gut conditions specifically. Take on an empty stomach when possible.

🔀 Common Stacks

+ TB-500

The most popular healing stack. TB-500 works systemically on actin and cytoskeletal repair while BPC-157 promotes angiogenesis and receptor upregulation. Together they address healing from multiple pathways. Typical: BPC-157 250 mcg 2×/day + TB-500 2.5 mg 2×/week.

+ Ipamorelin / CJC-1295

Adding a GH secretagogue amplifies recovery by increasing GH/IGF-1 — the body's primary anabolic and repair signals. Good stack for athletes recovering from serious injury.

❓ Frequently Asked Questions

What injuries respond best to BPC-157?

Tendon and ligament injuries show the strongest response in research — rotator cuff, Achilles, patellar tendon, and joint injuries. Muscle tears, gut inflammation (IBD, ulcerative colitis, leaky gut), and bone fractures also respond well. Less evidence for purely neurological applications, though some research is promising.

Should I inject SubQ or IM?

For systemic effects (gut healing, general recovery, inflammation): SubQ anywhere — abdomen is easiest. For local injury: IM injection near or into the affected tissue (e.g., IM near a damaged tendon). Both routes are used clinically.

Can I take BPC-157 orally?

Yes — BPC-157 is one of the few peptides with demonstrated oral bioavailability, likely because it is derived from a gastric protein. Oral dosing is primarily effective for gut and GI conditions. For systemic or musculoskeletal effects, injection is more reliable.

How long until I notice results?

Acute injuries often show improvement within 1–2 weeks. Chronic conditions may take 4–6 weeks of consistent use. Gut conditions frequently respond faster (3–7 days). Full tissue healing still requires adequate rest and physical therapy alongside peptide use.

Are there any side effects?

BPC-157 has an exceptional safety profile in animal studies. Human reports are generally of nausea (especially at high doses), mild dizziness, or injection site irritation. No serious adverse events have been reported in peer-reviewed literature.